Stool microsampling,
made effortless.

Hygienic, stabilised at-home stool collection for microbiome sequencing and colorectal screening (no mess, no cold chain, full chain of custody).

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Defined

What is stool
microsampling?

Stool microsampling is the remote, patient-collected, controlled-volume collection of a stabilised stool sample at home (gathered with a guided, hygienic device and returned to an accredited lab under documented chain of custody). The stabilising buffer preserves microbial DNA and faecal biomarkers at room temperature, with no refrigeration required. For stool, “micro” denotes a controlled, standardised small-volume collection into a stabilising buffer (typically milligrams to grams, not literal microlitres) the microsampling model applied to the gut.

□ Photo · Stool collection kit
Just the collection tube and buffered kit on a clean neutral surface (product-only, nothing graphic). Studio macro, soft light.
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How it works

From collection to lab.

01Collect

A guided, hygienic swab or scoop into a tube pre-filled with stabilising buffer. Clean, simple, under a minute.

02Seal & return

Sealed, ID-matched and returned by standard tracked DHL (no cold chain, the buffer protects the sample at room temperature).

03Result

Accessioned under full custody and reported into your system.

□ Photo · Collection in progress
A short, calm clip or photo of the collection journey for this matrix (collect, seal, hand to courier). Editorial, soft light.
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What it measures

A validated panel.

Microbiome16S and shotgun metagenomic sequencing of gut microbial DNA
Colorectal screeningFaecal immunochemical test (FIT) for occult blood
Gut inflammationCalprotectin and inflammatory markers
Why this matrix

Why it works now.

The barrier to stool microsampling was never the science (it was the experience and the cold chain). A stabilising buffer removes both: the sample is clean to collect, ships at room temperature, and preserves microbial DNA intact. That turns one-off diagnostics into longitudinal gut-health tracking, and makes population-scale colorectal screening logistically simple.

Clinical-grade by design

Sealed. Tracked.
Temperature-logged.

DNA-stabilising buffers preserve microbial and biomarker integrity at ambient temperature; the sample is sealed, ID-matched and DHL-tracked to the lab as a CE-marked IVD component, validated for the intended sequencing or immunochemical assay.

□ Photo · Chain of custody
A sealed, ID-labelled kit, a temperature logger, or the DHL handoff, the moment that proves clinical-grade. Shared across all sample pages.
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The kit

What's in the box.

□ Photo · Stool kit
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Stool collection kit

  • Hygienic swab or scoop
  • Buffered collection tube
  • Sealed return packaging
  • Instructions
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Who it's for

Whoever runs the test.

LaboratoriesScale microbiome sequencing and FIT screening
Pharma & CROMicrobiome endpoints in decentralised trials
Digital healthRun gut-health programmes end to end
Public healthColorectal screening at population scale

Infrastructure for healthcare and life sciences. Our partners reach the patient, and we never sell directly.

Good to know.

Does the sample need refrigeration?

No (the stabilising buffer preserves microbial DNA and biomarkers at room temperature, so it ships by standard tracked return).

Is it suitable for cancer screening?

Yes (FIT-based occult-blood collection is supported within accredited colorectal screening pathways, under documented chain of custody).

What can stool microsampling measure?

Gut microbiome by 16S and shotgun metagenomics, faecal occult blood by FIT, and inflammation markers such as calprotectin.

Is the collection hygienic?

Yes (the guided swab-or-scoop device is designed for clean, contained collection into a sealed, buffered tube).

The evidence

The research library.

8 papers

Sample type

Device

Topic

Access

PediatricsOMNIgene·GUT
An ambient-temperature stabilisation device performs comparably to flash-frozen collection for stool metabolomics in infantsRamamoorthy et al. · BMC Microbiology · 2021 · Open accessAn ambient-temperature DNA Genotek device recovered 94.5% of the metabolites seen in flash-frozen aliquots with strong agreement (room-temperature stabilisation can stand in for immediate freezing).Open-access full text (PDF)
Toward a human whole-stool reference material for metabolomic and metagenomic gut-microbiome measurementsMandal et al. · Metabolomics · 2020 · Open accessA multi-institution workshop made the case for a characterised whole-stool reference material so microbiome measurements can be standardised across labs (addressing the absence of defined faecal inputs).Open-access full text (PDF)
Impact of sampling regions and storage methods on fecal gut microbiome and metabolome profilesLiang et al. · mSphere · 2020 · Open accessSampling region barely affected community structure but strongly changed metabolite profiles, and homogenising the stool was essential for reproducible metabolomics (underscoring standardised, defined preparation).Open-access full text (PDF)
OMNIgene·GUT
Gut microbiome comparability of fresh-frozen versus stabilised-frozen samples by 16S and shotgun metagenomicsIlett et al. · Scientific Reports · 2019 · Open accessStool stabilised in OMNIgene·GUT then frozen produced 16S and shotgun profiles statistically indistinguishable from fresh-frozen aliquots (supporting stabilised collection where freezing is impractical).Open-access full text (PDF)
Evaluation of Interventions Intended to Increase Colorectal Cancer Screening Rates in the United States: A Systematic Review and Meta-analysisDougherty et al. · JAMA Internal Medicine · 2018 · PaywalledA systematic review and meta-analysis of interventions to raise colorectal cancer screening participation, including mailed outreach of home collection kits.
Quantitative microbiome profiling links gut community variation to microbial loadVandeputte et al. · Nature · 2017 · PaywalledExpressing taxa as cells per gram of stool showed faecal microbial load varies ~10-fold between healthy people and drives apparent compositional differences (relative-abundance data alone can misrepresent quantitative change).
Feasibility of self-collection of fecal specimens by randomly sampled women for gut-microbiome studiesFeigelson et al. · BMC Research Notes · 2014 · Open accessMailed at-home stool self-collection was feasible: ~20% of those approached enrolled and ~80% of those returned a usable specimen (workable, but recruitment depends on active, well-timed follow-up).Open-access full text (PDF)
Accuracy of Fecal Immunochemical Tests for Colorectal Cancer: Systematic Review and Meta-analysisLee et al. · Annals of Internal Medicine · 2014 · Open accessPooling 19 studies, FIT for colorectal cancer showed ~0.79 sensitivity and ~0.94 specificity (a moderately sensitive, highly specific single-sample stool screen, dependent on the positivity cut-off).Open-access full text (PDF)

External links open an open-access full text where one exists, otherwise the publisher or PubMed record. These citations describe the published evidence for the collection formats and devices (not claims about specific Humans Nexus assays, which are validated per analyte and per laboratory).

Put stool on the platform.

Talk to us about adding stool collection to your programme.

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