Saliva microsampling,
no needle, just spit.

Non-invasive oral-fluid collection (clinical-grade results for hormones, infectious disease and DNA, without a clinic).

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Defined

What is saliva
microsampling?

Saliva microsampling is the remote, patient-collected, volumetric collection of a clinical-grade oral-fluid sample at home (with no needle and no appointment) returned to an accredited lab under documented chain of custody. It is the microsampling model (patient-collected, small-format, through the platform) applied to saliva.

□ Photo · Saliva collection device
A clean editorial macro of the saliva swab / passive-drool tube, or a calm hand-to-mouth collection moment. Shallow depth of field, soft natural light, same language as the hero.
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How it works

From collection to lab.

01Collect

A guided swab between cheek and gum, or a passive-drool sample into a stabilising tube, in under two minutes. No needle, no clinician.

02Seal & return

The kit is sealed, ID-matched and returned by tracked DHL, temperature-logged where the panel requires it.

03Result

The lab accessions the sample under full chain of custody and reports straight into your system.

□ Photo · Collection in progress
A short, calm clip or photo of the collection journey for this matrix (collect, seal, hand to courier). Editorial, soft light.
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What it measures

A validated panel.

Steroid hormonesCortisol, cortisone, testosterone, DHEA, diurnal profiling across the day
Infectious diseaseViral and bacterial nucleic acid; antibody screening
GeneticsGermline DNA for pharmacogenomics and screening
Why this matrix

Why saliva.

For the free, biologically active fraction of steroid hormones, saliva is often the better matrix than blood, and it lets a patient capture a multi-point daily cortisol curve at home, something a venous draw can't practically do. Saliva microsampling also reaches the patients blood draws lose: children, the needle-averse, the remote.

Clinical-grade by design

Sealed. Tracked.
Temperature-logged.

Stabilising media preserve hormone and nucleic-acid integrity from the moment of collection. Every sample is sealed, ID-matched, DHL-tracked and temperature-logged through to accessioning, validated as CE-marked IVD components within the kit.

□ Photo · Chain of custody
A sealed, ID-labelled kit, a temperature logger, or the DHL handoff, the moment that proves clinical-grade. Shared across all sample pages.
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The kit

What's in the box.

□ Photo · Saliva kit
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Saliva collection kit

  • Swab or passive-drool device
  • Stabilising collection tube
  • Return packaging
  • App-guided instructions
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Who it's for

Whoever runs the test.

LaboratoriesExtend hormone and infectious-disease menus to remote collection
Pharma & CROCapture stress and endocrine endpoints without clinic visits
Digital healthOffer at-home hormone testing inside your app
InsurersUnderwrite from cortisol and biomarker data

Infrastructure for healthcare and life sciences. Our partners reach the patient, and we never sell directly.

Good to know.

Is saliva as reliable as blood for hormones?

For the free-fraction steroid hormones (cortisol, testosterone) saliva is often the preferred matrix: it reflects the biologically active, unbound hormone and enables non-invasive, multi-point daily sampling a venous draw can't match.

Which analytes can saliva measure?

Steroid hormones, viral and bacterial nucleic acid, antibodies, and germline DNA for pharmacogenomics, all from a single at-home collection.

How is the sample kept stable in transit?

Stabilising tubes preserve hormone and nucleic-acid integrity at ambient temperature, with controlled-temperature logging applied to sensitive panels.

Who collects the sample?

The patient, at home, guided step by step, no phlebotomist and no clinic visit.

The evidence

The research library.

9 papers

Sample type

Device

Topic

Access

Utility of Salivary Cortisol and Cortisone in the Diagnostics of Adrenal InsufficiencyKvam Hellan et al. · Journal of Clinical Endocrinology & Metabolism · 2025 · PaywalledSalivary cortisol and cortisone assessed for diagnosing adrenal insufficiency (clinical utility for a saliva analyte, not only stabilisation of the matrix).
Non-invasive assessment of free steroid hormones: a high-throughput LC-MS/MS method for salivary steroid quantificationSlettvoll et al. · Analytical and Bioanalytical Chemistry · 2025 · Open accessTestosterone, androstenedione, cortisol and cortisone were measurable from 200 µL saliva, but estradiol fell below quantification and progesterone in under half of samples (only a subset of steroids is reliable in saliva, and not interchangeable with serum).Open-access full text (PDF)
Saliva sampling method influences oral microbiome composition and taxa associated with oral diseasesRoca et al. · PLoS ONE · 2024 · Open accessHow saliva is collected changes the microbiome result (stimulated collection surfaced disease-associated taxa that unstimulated missed) so the protocol must be standardised before results can be compared.Open-access full text (PDF)
Factors influencing oral microbiome analysis: from saliva sampling to sequencing platformsBang et al. · Scientific Reports · 2023 · Open accessBoth collection method and sequencing platform shape the measured salivary microbiome, though three stabilisation media gave comparable diversity (method must be held constant across a cohort).Open-access full text (PDF)
Pediatrics
Reliability of Salivary versus Serum Cortisol for Diagnosing Adrenal Insufficiency in ChildrenCiancia et al. · Children · 2023 · Open accessDuring ACTH stimulation, salivary cortisol correlated only weakly with serum and gave modest accuracy (saliva does not reliably replace serum cortisol for adrenal insufficiency). A concrete limit.Open-access full text (PDF)
Prospective Evaluation of Late-Night Salivary Cortisol and Cortisone in Suspected Cushing SyndromeKannankeril et al. · J. Endocrine Society · 2020 · Open accessLate-night salivary cortisol was a highly sensitive screen (~97%) for ACTH-dependent Cushing syndrome, but performed poorly for adrenal disease (a validated screening, not confirmatory, test).Open-access full text (PDF)
ORAcollect
Saliva DNA quality and genotyping efficiency in a predominantly elderly populationGudiseva et al. · BMC Medical Genomics · 2016 · Open accessWith Oragene DISCOVER self-collection, saliva SNP-array genotypes matched blood at 99.996% concordance; about 6% of samples failed on low yield, so an occasional repeat should be expected.Open-access full text (PDF)
ORAcollect
Validation of saliva as an alternative specimen for detecting hereditary breast-cancer mutations by next-generation sequencingMeghnani et al. · International J. Genomics · 2016 · Open accessORAcollect saliva matched blood at 97.9% overall variant concordance on a hereditary-cancer NGS panel, rising to 100% for protein-coding variants (supporting self-collected saliva for germline testing).Open-access full text (PDF)
ORAcollect
Genotyping Performance between Saliva and Blood-Derived Genomic DNAs on the DMET Array: A ComparisonHu et al. · PLoS ONE · 2012 · Open accessOragene-stabilised saliva DNA agreed with blood at 98.7% of called markers on a pharmacogenetic array; saliva's lower overall call rate tracked its variable human-DNA content.Open-access full text (PDF)

External links open an open-access full text where one exists, otherwise the publisher or PubMed record. These citations describe the published evidence for the collection formats and devices (not claims about specific Humans Nexus assays, which are validated per analyte and per laboratory).

Put saliva on the platform.

Talk to us about adding saliva collection to your programme.

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