The first blood test,
without the first tear.

Every parent knows the sound of needle fear: the gripped sleeve, the night-before dread. For children, and for anyone with needle phobia or a learning disability, the venepuncture chair is where healthcare breaks down. Pediatric microsampling rewrites the scene: a small touch-activated device on the upper arm, applied by a healthcare professional, a halo of microneedles, not a blade. No white knuckles. No held-down child. A blood test that ends in a sticker, not a tear.

Talk to salesSee how →
Stickers first. Then the arm.
Why children

Small veins, big fear.

A TAP capillary collector on a newborn's upper arm during a blood collection
On a newborn, where a heel prick would otherwise be the only option.
A child having a capillary blood sample collected from the upper arm with a TAP device
On the upper arm, without a phlebotomist and without a needle in view.
A TAP collection device decorated with children's stickers
Decorated by the child it belongs to. Children describe it as a sticker.

A child doesn’t remember the diagnosis. They remember being held down. Pediatric venipuncture fails where it hurts most: small veins mean repeat attempts, repeat attempts mean restraint, and restraint teaches a child that medicine is something done to them. So parents postpone the next test, and the clinical picture goes blank exactly where growing bodies change fastest.

The fear compoundsNeedle phobia formed at six follows a patient for sixty years, every skipped test starts here.
Veins don’t cooperatePediatric draws routinely take more than one attempt. Each attempt costs blood, time and trust.
Care goes blindPostponed tests and under-recruited pediatric trials leave children’s medicine running on less data than any other age group.
The device

Stickers on, fear off.

The platform’s answer is YourBio TAP, touch-activated and applied to the upper arm, a halo of microneedles, not a blade. In a peer-reviewed study, most participants preferred it to a needle, 63% versus 7%. The children decorate the device with stickers before it goes on, a healthcare professional applies it with the parent right there, and the sample is done before the fear has anywhere to start. For infants, collection is demonstrated from the thigh, held in a parent’s arms. In children the device is used under healthcare-professional supervision; at-home self-collection is for adults.

The YourBio device on the platform →

A clinician’s hands. A parent beside.
A true story · in the NHS

“Great fun,” said Abi.
About a blood test.

Abi is fifteen. She has Down’s syndrome, and her thyroxine treatment needs regular blood monitoring, which for years meant everything a needle means to a frightened teenager. Then University Hospitals of Morecambe Bay NHS Foundation Trust became the first NHS trust to offer TAP collection for people with learning disabilities, in a programme led by Karen Perkins, Principal Clinical Scientist. Since April 2025 the team has collected samples from nearly fifty patients who previously could not give blood at all, and six more NHS trusts have asked for their data to replicate the model.

~50patients who previously couldn’t give blood, sampled since April 2025
6more NHS trusts asking for the data to replicate the model
1stNHS trust to offer TAP for people with learning disabilities

“TAP really is a game changer for Abi, and I’m sure many others like her.”

Abi’s mother · University Hospitals of Morecambe Bay NHS Foundation Trust

“The fear of your child dying never goes away. Now I know I can keep her well.”

Lucy’s mother · Lucy, 16, has Down’s syndrome and autism · University Hospitals of Morecambe Bay NHS Foundation Trust

Abigail's StoryBlood Sciences, University Hospitals of Morecambe Bay NHS Foundation Trust · 5:09

Nothing loads from YouTube until you press play: no third-party request, no cookie, before that. The film is Blood Sciences, University Hospitals of Morecambe Bay NHS Foundation Trust’s, not ours. Watch it on YouTube →

Read the story at the Royal College of Pathologists  ·  the Trust’s announcement

Quotes and figures from the Royal College of Pathologists and University Hospitals of Morecambe Bay NHS Foundation Trust. TAP is the YourBio device curated on the Humans Nexus platform; the Morecambe Bay programme is the Trust’s own work. Pediatric microsampling and paediatric microsampling are the same practice, the American and British spellings of one idea.

The evidence

Not a promise. A record.

We won’t ask you to take virtually painless on faith or put a stronger word in anyone’s mouth: what follows comes from independent, peer-reviewed research and the clinicians who use it, and every paper is in our research library. In an Oxford trial published in Diabetes Care, 63% of participants, children and adults, preferred the device to a needle and just 7% preferred the needle; Oxford judged it a reliable, highly accurate alternative to a venous draw, with far less post-collection bruising, about 6% versus 35% after a needle. At Massachusetts General Hospital, published in JAMA, it drew blood from infants as young as two months, chosen to avoid a painful heel prick.

63%preferred it to a needle, just 7% preferred the needleBesser et al. · Diabetes Care 2024
100%sensitivity & specificity for detecting a clinically relevant C-peptide level, 200 pmol/L or moreBesser et al. · Diabetes Care 2024
2 mothe youngest infants sampled, to avoid a heel prickMGH / Edlow Lab · JAMA 2022

“We are using a microneedle sticker device that collects surface capillary blood from the babies in order to avoid a painful heel prick/venipuncture.”

Edlow Lab · Massachusetts General Hospital · edlowlab.org
Independent & peer-reviewed
PediatricsYourBio
Transdermal blood sampling for C-peptide is a minimally invasive, reliable alternative to venous sampling in children and adults with type 1 diabetesBesser et al. · Diabetes Care 2024;47(2):239 · Oxford University Hospitals91 participants, children and adults. Capillary C-peptide from the TAP device matched venous results with 100% sensitivity and specificity for detecting a clinically relevant level, 200 pmol/L or more, with a correlation of 0.996; 63% preferred it to a needle and just 7% preferred the needle, and post-collection bruising was far less common than after a venous draw, 5.5% versus 34.8% on the day of collection.Open-access full text, PDF
PediatricsYourBio
Durability of anti-spike antibodies in infants after maternal COVID-19 vaccination or natural infectionShook, Edlow et al. · JAMA 2022 · Massachusetts General HospitalThe paper states the TAP II blood-collection devices for the infant draws were provided by YourBio Health; capillary serum was collected from babies as young as two months, the smallest patients, sampled without a heel prick or a venipuncture.Open-access full text, PDF
PediatricsYourBio
O’Ryan.Health launches parent-led pediatric studies using YourBio TAPPR Newswire · 31 July 2024 · O’Ryan.Health & YourBio HealthTwo IRB-approved observational studies, one in ultra-rare juvenile dermatomyositis, built on capillary blood collected from children, on a schedule, without a trip to the clinic.

These are independent studies of the YourBio TAP device that Humans Nexus curates on its platform, not our own trials; the maker supplied the devices but, per the papers, had no role in their design or analysis. On the Humans Nexus platform, children are collected under healthcare-professional supervision; the at-home collections above were conducted within IRB-approved research protocols.

Also on the platform · dried blood

For the children who need it often.

The lancet-free upper-arm draw is one path. For a child with a chronic condition, a transplant, an autoimmune disease, who needs a drug level checked again and again, the platform also offers the Neoteryx Mitra device: a fixed-volume dried-blood microsample from a single fingertip, taken at home instead of a repeat venous draw. A different tool for a different job, quantitative drug monitoring, and the evidence in children is real.

r = 0.95home dried-blood agreed with a clinic venous draw for tacrolimusZhao et al. · pediatric heart transplant · 2023
83%of families found home sampling easy, and would do it againZhao et al. · satisfaction survey
0children who declined to keep collecting at homeZhao et al. · 2023

Validated in children for transplant immunosuppressants and antifungal drug levels. The Mitra device on the platform →

OpenSampling Library by Humans Nexus

Library VAMS in children

Peer-reviewed evidence for volumetric absorptive microsampling (VAMS) in pediatric drug monitoring: at-home tacrolimus after transplant, antifungal levels, and the honest limits. Every paper opens its page in the OpenSampling Library, with a link to an open-access copy where one exists.

  1. Cefepime pharmacokinetics in critically ill children with multiple organ dysfunction syndrome using volumetric absorptive microsampling

    Antimicrobial agents and chemotherapy · 2026 · Open access

    In 15 critically ill children with multiple organ dysfunction, a population pharmacokinetic model built on volumetric absorptive microsamples found that estimated glomerular

    Read in the Library

  2. Volumetric Absorptive Microsampling (VAMS) for Therapeutic Drug Monitoring of Antiseizure Medications (ASMs) in Pediatric Patients

    Pharmaceuticals · 2026 · Paywalled

    This study found that volumetric absorptive microsampling shows satisfactory agreement with venous plasma for monitoring several antiseizure medications in paediatric patients. However, a blood-to-plasma conversion factor was required to estimate plasma concentrations

    Read in the Library

  3. Analytical validation of a dried blood microsampling method to measure androstenedione, 17α‑hydroxyprogesterone, and 11‑ketotestosterone for congenital adrenal hyperplasia monitoring

    Talanta · 2026 · Paywalled

    A liquid chromatography-tandem mass spectrometry method was successfully validated for measuring androstenedione, 17α-hydroxyprogesterone, and 11-ketotestosterone in dried blood samples collected via volumetric absorptive microsampling. The dried samples remained stable at room temperature for up to a week and after postal transit, and

    Read in the Library

  4. Systematic evaluation of propofol population pharmacokinetic models and development of a literature-supported new meta-model for critically ill preterm and term neonates

    European journal of pharmaceutical sciences · 2026 · Paywalled

    This study employed volumetric absorptive microsampling to collect blood samples from neonates, revealing that existing propofol pharmacokinetic models poorly predicted drug levels in this population. A newly developed meta-model provided accurate predictions, validating the use of

    Read in the Library

  5. Development and application of an LC-MS/MS method for 8 antiepileptic drugs and 2 metabolites using microsampling techniques (DBS and VAMS)

    Journal of analytical toxicology · 2026 · Open access

    The study validated an LC-MS/MS method for eight antiepileptic drugs and two metabolites in dried blood spot and VAMS formats, with satisfactory analytical performance and stability, and was the first to include the oxcarbazepine metabolite DHCB. In 80 paired patient samples, microsampling concentrations showed promising correlation

    Read in the Library

  6. Rapid, robust LC-MS/MS quantification of cefazolin in whole blood microsamples, plasma, and plasma ultrafiltrate: Analytical method validation and preliminary clinical application in pediatric population

    Clinica chimica acta · 2026 · Paywalled

    The study developed and validated a rapid LC-MS/MS method for quantifying cefazolin in capillary whole blood collected via VAMS, plasma, and plasma ultrafiltrate, showing robust performance across matrices and

    Read in the Library

All 59 in the OpenSampling Library

These citations describe the published evidence for the collection formats and devices, not claims about specific Humans Nexus assays, which are validated per analyte and per laboratory.

Held by a parent. Not a clinic.
Under supervision

A clinician’s hands, a guided Flow.

For children, collection happens under healthcare-professional supervision: at the practice, on the ward, at the point of care or on a supervised home-nursing visit. Flow carries the record: identity attested, consent recorded by the parent or guardian, collection confirmed. From there the sample follows the same route as every other, clinical courier pickup, documented chain of custody, an accredited laboratory, and the result returns to the pediatrician and the family under the programme’s release policy. At-home self-collection with YourBio is for adults.

You stay in the room. The stickers are her job; the rest is ours.

Flow, the patient companion →  ·  Identity & consent →

What it unlocks

Pediatric care, finally seen.

Pediatric trialsVisits families stop dreading: a gentle draw instead of a cannula, and cohorts that stay
Chronic pediatric careEndocrinology, allergy and drug monitoring between visits, without a fight, without a gap
Infant follow-upRepeat sampling after newborn screening, without another venepuncture
Needle phobia & learning disabilitiesThe patients conventional phlebotomy leaves behind, as the NHS is now proving
The draw that ends with a smile.

Good to know.

Is there a needle-free blood test for children?

Not needle-free, but there is no lancet and no venepuncture, which is the distinction that matters to a frightened child. TAP collects from the upper arm through a halo of microneedles rather than a blade: nothing to watch go in, and no fingertip squeeze. Applied by a healthcare professional, it draws a real whole-blood sample the laboratory runs like any other. It’s decorated with stickers before it goes on, and in published studies most participants preferred it to a needle.

Is it really virtually painless for children?

The evidence is independent. In an Oxford trial published in Diabetes Care, most participants, children and adults, preferred it to a needle, 63% against 7%, and Oxford judged it a reliable, highly accurate alternative. At Massachusetts General Hospital, clinicians use it on infants specifically to avoid a painful heel prick. In the NHS programme, Abi called it great fun. There is no lancet, no visible needle and no venepuncture.

Does it work for needle phobia or learning disabilities?

That is where it has proven itself most. University Hospitals of Morecambe Bay NHS Foundation Trust, the first NHS trust to offer TAP for people with learning disabilities, has collected from nearly fifty patients since April 2025 who previously could not give blood at all, and other trusts are adopting the model.

What ages can use it?

The manufacturer demonstrates use across ages: upper-arm collection for children and adults, and thigh collection for infants held by a parent. In children the device is used under healthcare-professional supervision; adults may self-collect at home. Suitability for a specific programme and age group is confirmed per protocol with the laboratory.

Who collects the sample?

For children, a healthcare professional, at the practice, the point of care or a supervised visit, with the parent alongside and consent recorded by the parent or guardian in Flow. At-home self-collection with YourBio is for adults.

What can be tested?

The device collects liquid whole blood, the same matrix as a venous draw, in microsample volume, suitable for a broad validated panel confirmed with the accredited laboratory, from thyroid monitoring to drug levels.

How does the sample travel?

Like every sample the platform tracks: clinical courier pickup, temperature-managed where the assay requires it, documented chain of custody from collection to laboratory accessioning.

OpenSampling Library by Humans Nexus

Library Capillary blood in children

The peer-reviewed record for capillary blood in children and adolescents: the TAP device studies, agreement with venous sampling for drug levels, antibodies and biomarkers across upper-arm, fingerstick and dried formats, and the honest limits. Every paper opens its page in the OpenSampling Library, with a link to an open-access copy where one exists.

Newest

  1. Serial Dried Blood Spot C-Peptide Sampling, but Not Urine C-Peptide-to-Creatinine Ratio, Detects Early Preservation of β-Cell Function in New-Onset Type 1 Diabetes: Experience From the USTEKID Trial

    Diabetes care · 2026 · Paywalled

    Frequent dried blood spot sampling detected early changes in beta-cell function more effectively than mixed-meal tolerance tests or urine ratios, supporting its

    Read in the Library

  2. Minimally Invasive Therapeutic Drug Monitoring of Immunosuppressants in Children with Kidney Diseases: Validation of Fingerstick Sampling Using LC-MS/MS

    Pharmaceuticals · 2026 · Open access

    Fingerstick capillary sampling showed strong agreement with venous sampling for mycophenolic acid, tacrolimus and cyclosporine A, with acceptable bias and improved agreement for mycophenolic acid after haematocrit correction. This minimally invasive approach may reduce procedural burden and

    Read in the Library

  3. Feasibility verification of fingerstick capillary microsampling replacing venipuncture for therapeutic drug monitoring of 12 antibiotics using a rapid LC-MS/MS assay

    Talanta · 2026 · Paywalled

    This study validated a method requiring only 10 microlitres of serum and found high agreement between fingerstick capillary samples and venous serum for monitoring twelve antibiotics. The results suggest capillary serum sampling is a feasible, minimally invasive

    Read in the Library

  4. Rapid, robust LC-MS/MS quantification of cefazolin in whole blood microsamples, plasma, and plasma ultrafiltrate: Analytical method validation and preliminary clinical application in pediatric population

    Clinica chimica acta · 2026 · Paywalled

    The study developed and validated a rapid LC-MS/MS method for quantifying cefazolin in capillary whole blood collected via VAMS, plasma, and plasma ultrafiltrate, showing robust performance across matrices and

    Read in the Library

  5. Neonatal Capillary Blood Sampling Procedure: A Scoping Review

    Hospital pediatrics · 2026 · Paywalled

    Neonatal capillary blood sampling procedures are reported inconsistently, with pain and sample quality as primary outcomes. Inconsistent reporting of decontamination, supportive care, and device use impedes

    Read in the Library

  6. Population pharmacokinetic modeling and simulation-informed ceftazidime dosing in Chinese neonates using quantitative dried blood spot micro-sampling

    Antimicrobial agents and chemotherapy · 2026 · Open access

    Using quantitative dried blood spot microsampling from 72 neonates, the authors developed a population pharmacokinetic model for ceftazidime that identified postmenstrual age and body weight as significant covariates influencing drug clearance and volume of distribution. Monte Carlo simulations supported dosing regimens of 25 mg/kg every 6-8 hours or 75 mg/kg every 12 hours for neonates

    Read in the Library

All 75 in the OpenSampling Library

Agreement vs venous

  1. Minimally Invasive Therapeutic Drug Monitoring of Immunosuppressants in Children with Kidney Diseases: Validation of Fingerstick Sampling Using LC-MS/MS

    Pharmaceuticals · 2026 · Open access

    Fingerstick capillary sampling showed strong agreement with venous sampling for mycophenolic acid, tacrolimus and cyclosporine A, with acceptable bias and improved agreement for mycophenolic acid after haematocrit correction. This minimally invasive approach may reduce procedural burden and

    Read in the Library

  2. Feasibility verification of fingerstick capillary microsampling replacing venipuncture for therapeutic drug monitoring of 12 antibiotics using a rapid LC-MS/MS assay

    Talanta · 2026 · Paywalled

    This study validated a method requiring only 10 microlitres of serum and found high agreement between fingerstick capillary samples and venous serum for monitoring twelve antibiotics. The results suggest capillary serum sampling is a feasible, minimally invasive

    Read in the Library

  3. Analytical validation of capillary blood Krebs von den Lungen-6 measurement using a high- sensitivity chemiluminescent immunoassay in pediatric patients

    Frontiers in medicine · 2026 · Open access

    Haematocrit correction of capillary blood samples reduced the mean bias against venous plasma from -48.32 to -3.47 U/mL and improved the Pearson correlation coefficient from 0.958 to 0.966 in 80 paired pediatric samples, with excellent repeatability (CV <3%). This demonstrates analytical feasibility of patient-centric microsampling for

    Read in the Library

  4. The Impact of Age, Comorbidity, and Current Medication Use on Plasma p-tau217 in Adolescents: A Pilot Study

    The journal of applied laboratory medicine · 2026 · Paywalled

    In a pilot study of 41 adolescents, plasma p-tau217 concentrations did not associate with age, comorbidity or medication use. However, concentrations from Tasso+ capillary blood were 10-fold higher than from venous blood, a discrepancy also seen

    Read in the Library

  5. Comparison between point-of-care testing from capillary samples and conventional laboratory testing from venous samples for white blood cells and C-reactive protein in a pediatric outpatient setting

    Journal of general and family medicine · 2025 · Open access

    In 277 paediatric patients, capillary microsampling with the Microsemi CRP device found close agreement with venous testing for CRP, with a mean difference of -0.25 mg/dL and 95% limits of -2.1 to 1.6 mg/dL. WBC showed a bias of -18 × 100/μL, with 95% limits of -73 to 37 × 100/μL.

    Read in the Library

  6. Evaluation of SARS-CoV-2 Antibody Response Between Paired Fingerprick (HemaPEN®) and Venepuncture Collected Samples in Children and Adults

    Antibodies · 2025 · Open access

    This study found moderate to strong correlations between SARS-CoV-2 antibody levels in fingerprick dried blood spots collected using the hemaPEN device and standard venous serum samples from children and adults. The results suggest that this microsampling device offers a

    Read in the Library

All 45 in the OpenSampling Library

Therapeutic drug monitoring

  1. Minimally Invasive Therapeutic Drug Monitoring of Immunosuppressants in Children with Kidney Diseases: Validation of Fingerstick Sampling Using LC-MS/MS

    Pharmaceuticals · 2026 · Open access

    Fingerstick capillary sampling showed strong agreement with venous sampling for mycophenolic acid, tacrolimus and cyclosporine A, with acceptable bias and improved agreement for mycophenolic acid after haematocrit correction. This minimally invasive approach may reduce procedural burden and

    Read in the Library

  2. Feasibility verification of fingerstick capillary microsampling replacing venipuncture for therapeutic drug monitoring of 12 antibiotics using a rapid LC-MS/MS assay

    Talanta · 2026 · Paywalled

    This study validated a method requiring only 10 microlitres of serum and found high agreement between fingerstick capillary samples and venous serum for monitoring twelve antibiotics. The results suggest capillary serum sampling is a feasible, minimally invasive

    Read in the Library

  3. Rapid, robust LC-MS/MS quantification of cefazolin in whole blood microsamples, plasma, and plasma ultrafiltrate: Analytical method validation and preliminary clinical application in pediatric population

    Clinica chimica acta · 2026 · Paywalled

    The study developed and validated a rapid LC-MS/MS method for quantifying cefazolin in capillary whole blood collected via VAMS, plasma, and plasma ultrafiltrate, showing robust performance across matrices and

    Read in the Library

  4. Population pharmacokinetic modeling and simulation-informed ceftazidime dosing in Chinese neonates using quantitative dried blood spot micro-sampling

    Antimicrobial agents and chemotherapy · 2026 · Open access

    Using quantitative dried blood spot microsampling from 72 neonates, the authors developed a population pharmacokinetic model for ceftazidime that identified postmenstrual age and body weight as significant covariates influencing drug clearance and volume of distribution. Monte Carlo simulations supported dosing regimens of 25 mg/kg every 6-8 hours or 75 mg/kg every 12 hours for neonates

    Read in the Library

  5. Volumetric Absorptive Microsampling of Saliva for Pharmacokinetic Evaluation of Mycophenolic Acid and Its Glucuronide Metabolite in Pediatric Renal Transplant Recipients: Bioanalytical Method Validation and Clinical Feasibility Evaluation

    Pharmaceuticals · 2025 · Open access

    Dried saliva collected with the Mitra device correlated strongly with wet saliva but poorly with plasma unbound and total concentrations, indicating it is not a reliable substitute for plasma in routine therapeutic drug monitoring of mycophenolic acid and its glucuronide metabolite. Capillary blood collected via VAMS remains a promising

    Read in the Library

  6. The comparison of two volumetric microsampling devices (qDBS and VAMS) for determining ganciclovir levels in capillary blood using the LC-MS/MS technique in pediatric renal transplant recipients

    European journal of pharmaceutical sciences · 2025 · Paywalled

    The study compared quantitative dried blood spot (qDBS) and volumetric absorptive microsampling (VAMS) devices for measuring ganciclovir levels in capillary blood from pediatric renal transplant recipients. This comparison provides evidence for choosing between microsampling devices in therapeutic drug monitoring,

    Read in the Library

All 37 in the OpenSampling Library

Patient acceptability & preference

  1. Point-of-Care Testing in PKU: A New ERA of Blood Phenylalanine Monitoring

    Nutrients · 2025 · Open access

    The Egoo Phe system showed strong concordance with dried blood spot testing across 100 paired samples, with median phenylalanine 274 versus 270 μmol/L and readings a mean 4.6% higher, and high caregiver

    Read in the Library

  2. Patient centric blood sampling and analysis for diagnostics and laboratory medicine

    Bioanalysis · 2025 · Open access

    A 2025 review maps 28 microsampling devices, from dried spots and volumetric absorptive tips to upper-arm liquid capillary collectors, and names what a laboratory must control before their results are used: the haematocrit effect in non-volumetric dried samples, interstitial fluid from finger milking, volume, haemolysis and transport stability. Regulators on both sides of the Atlantic ask for the same two

    Read in the Library

  3. Establishing the performance and acceptability of dried blood spot sampling to screen for islet-specific autoantibodies

    Diabetic medicine · 2025 · Open access

    Dried blood spot sampling matched venous serum performance for islet autoantibody detection and was considered minimally invasive and convenient by parents and stakeholders,

    Read in the Library

  4. Transdermal blood sampling for C-peptide is a minimally invasive, reliable alternative to venous sampling in children and adults with type 1 diabetes

    Diabetes Care · 2024 · Open access

    In 91 children and adults, capillary C-peptide taken with the TAP device matched venous sampling with 100% sensitivity and specificity for a clinically relevant level, 200 pmol/L or above, with r = 0.996. 63% preferred it to a needle

    Read in the Library

  5. Feasibility, acceptability and safety of a device for self-collecting capillary blood in clinical trials

    PLOS ONE · 2024 · Open access

    In at-home and trial settings, a wet capillary device reliably collected a median ~450 µL with a 4.4% failure rate; 88% of adults

    Read in the Library

  6. A Systematic Literature Review on the Use of Dried Biofluid Microsampling in Patients With Kidney Disease

    Journal of clinical laboratory analysis · 2024 · Open access

    This systematic review of 67 studies involving 34,739 kidney disease patients found dried blood microsampling was mainly used for immunosuppressant therapeutic drug monitoring and kidney function assessment. The approach offered cost savings, was preferred by patients for home self-collection, and provides a patient-centric

    Read in the Library

All 18 in the OpenSampling Library

Serology & infectious disease

  1. Evaluation of SARS-CoV-2 Antibody Response Between Paired Fingerprick (HemaPEN®) and Venepuncture Collected Samples in Children and Adults

    Antibodies · 2025 · Open access

    This study found moderate to strong correlations between SARS-CoV-2 antibody levels in fingerprick dried blood spots collected using the hemaPEN device and standard venous serum samples from children and adults. The results suggest that this microsampling device offers a

    Read in the Library

  2. Patient centric blood sampling and analysis for diagnostics and laboratory medicine

    Bioanalysis · 2025 · Open access

    A 2025 review maps 28 microsampling devices, from dried spots and volumetric absorptive tips to upper-arm liquid capillary collectors, and names what a laboratory must control before their results are used: the haematocrit effect in non-volumetric dried samples, interstitial fluid from finger milking, volume, haemolysis and transport stability. Regulators on both sides of the Atlantic ask for the same two

    Read in the Library

  3. Assessment of the performance of the plasma separation card for HIV-1 viral load monitoring in South Africa

    Journal of clinical microbiology · 2024 · Open access

    Plasma separation cards showed high specificity (99.3%) but moderate sensitivity (87.5%) against EDTA-plasma for HIV-1 viral load monitoring at a 1,000 copies/ml threshold in a South African cohort. Despite favourable usability among healthcare workers, laboratory-reported technical

    Read in the Library

  4. Durability of anti-spike antibodies in infants after maternal COVID-19 vaccination or natural infection

    JAMA · 2022 · Open access

    The paper records that the TAP II devices used for the infant draws were provided by YourBio Health, and that capillary serum was collected from babies as young as two

    Read in the Library

  5. Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Detect a SARS-CoV-2 Antibody Response

    Microbiology spectrum · 2022 · Open access

    In British Columbia, finger-prick dried blood spots had 97% specificity and 79% sensitivity for SARS-CoV-2 antibodies in unvaccinated groups, rising to 97 to 100% after vaccination, against serum; limited to one jurisdiction,

    Read in the Library

  6. Use of a commercial ELISA for the detection of measles-specific immunoglobulin G (IgG) in dried blood spots collected from children living in low-resource settings

    Journal of medical virology · 2015 · Paywalled

    The study validated a commercial ELISA for measuring measles-specific IgG in capillary dried blood spots from children, finding 100% sensitivity and 96.8% specificity against matched venous serum with 92% overall agreement, then applied the method to 1,588 field-collected samples in Mexico and Nicaragua. The procedure was acceptable to surveyors and participants, showing that dried blood spots are a

    Read in the Library

All 6 in the OpenSampling Library

YourBio TAP

  1. Transdermal blood sampling for C-peptide is a minimally invasive, reliable alternative to venous sampling in children and adults with type 1 diabetes

    Diabetes Care · 2024 · Open access

    In 91 children and adults, capillary C-peptide taken with the TAP device matched venous sampling with 100% sensitivity and specificity for a clinically relevant level, 200 pmol/L or above, with r = 0.996. 63% preferred it to a needle

    Read in the Library

  2. Durability of anti-spike antibodies in infants after maternal COVID-19 vaccination or natural infection

    JAMA · 2022 · Open access

    The paper records that the TAP II devices used for the infant draws were provided by YourBio Health, and that capillary serum was collected from babies as young as two

    Read in the Library

All 2 in the OpenSampling Library

These citations describe the published evidence for the collection formats and devices, not claims about specific Humans Nexus assays, which are validated per analyte and per laboratory.

Give pediatrics its data back.

Somewhere a parent is postponing a blood test their child needs. Build the programme that ends that: trials, chronic care or family health.

Talk to salesThe YourBio device →